**7. Conclusions**

This review highlights mouse models of monogenic retinal degenerative diseases that cause rod or cone PR cell loss. The models include germline mutations and conditional alleles, in which characterization of retinal phenotypes in germline mutations was not possible due to embryonic or perinatal lethality. By providing an extensive list of these models as well as a means of comparing their progression, we hope to benefit researchers who seek to optimize their experimental approaches.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/2073-4409/9/4/931/s1, Figure S1: OCT and fundus images of C57BL/6J control mice at various ages, Table S1: Monogenic mouse RD models with PR cell loss, Table S2: Description of gene/protein symbols used in the text and figures.

**Author Contributions:** Conceptualization, P.M.N., M.P.K.; methodology, M.P.K., B.C., P.M.N.; software, M.P.K.; formal analysis, M.P.K.; investigation, G.B.C., N.G., N.D., J.P., L.F.H., L.S., J.K.N., M.P.K., P.M.N.; resources, B.C., J.K.N., P.M.N.; data curation, G.B.C., N.G., N.D., J.P., L.F.H., L.S., J.K.N., M.P.K., P.M.N.; writing—original draft preparation, G.B.C., N.G., N.D., J.P., L.H., J.K.N., M.P.K., P.M.N.; writing—review and editing, G.B.C., N.G., J.K.N., M.P.K., P.M.N.; visualization, B.C., M.P.K.; supervision, J.K.N., P.M.N.; project administration, P.M.N.; funding acquisition, M.P.K., B.C., J.K.N., P.M.N. All authors have read and agree to the published version of the manuscript.

**Funding:** This work was funded in part by National Institutes of Health grants 5R01EY011996, 5R01EY027860, R01EY027305 (to P.M.N), 5R01EY028561 (to J.K.N.), 5R01EY019943 (to B.C.), and 5R21EY027894 (to M.P.K). N.D. was supported by the gran<sup>t</sup> from the Royal Golden Jubilee (RGJ) Scholarship (PHD/0102/2559), Thailand Research Fund.

**Acknowledgments:** The authors thank James Kadin and Grace Stafford for help with scripts to filter PubMed data, Cynthia Smith for her contributions to Table S1 and for coordinating our efforts with those at MGI, Melissa Berry for assistance with nomenclature, Bernard Fitzmaurice and Wanda Hicks for fundus and/or OCT imaging, and Jane Cha for drawing Figure 1.

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
