*2.4. Statistical Analysis*

The statistical analyses are performed with the one-way analysis of variance (ANOVA) using the prism software (GraphPad, San Diego, CA, USA). The data are reported as mean ± standard error, and *p*-values of \* *p* < 0.05, \*\* *p* < 0.01, \*\*\* *p* < 0.001 were considered statistically significant.

#### **3. Results**
