4.5.4. Anticoagulant Activity

Phlorotannins and sulfated polysaccharides such as fucoidans in brown algae, carrageenans in red algae, and ulvans in green algae have been recognized as potential anticoagulant agents [61–64]. For example, in a study carried out by [79], they tested the effect of some polysaccharides rich extracts obtained from green algae *Ulva fasciata* and red algae *Agardhiella subulata* in the thromboplastin time and prothrombin time, resulting that both algal extracts showed that prolong those mentioned times during the coagulation cascade, avoiding blood coagulation. However, the anticoagulant activity has been mainly investigated in vitro or in mouse. Hence, and due to the important value of that property, more studies are needed [62].
