*2.1. Supplies, Chemicals and Model Systems*

Culture medium, fetal bovine serum, and cell culture reagents were provided by Gibco (Biomol, Sevilla, Spain). The rest of the chemicals were purchased from Sigma-Aldrich (Madrid, Spain) and VWR International Eurolab (Barcelona, Spain).

The human cell lines Caco-2 and HepG2 were maintained as described in Gutierrez-Praena et al. (2012) [23].
