*2.11. Statistical Analysis*

The experimental results were expressed as the mean ± SD for the in vitro data and as the mean ± SEM for the in vivo data. One-way analysis of variance (ANOVA) was used for multiple comparisons (GraphPad Prism version 5.03 for Windows, San Diego, CA, USA). The Dunnett test and the Tukey's test were applied for significant variations between treated groups. Differences at the \* *p* < 0.05 and \*\* *p* < 0.01 levels were considered statistically significant.
