*7.3. Summary*

Overall, strategies to target IE2 function have identified a number of interesting compounds, although their exact mechanism of action has not been fully elucidated. To date, compounds that target IE1 function have not been identified, and IE1 remains an important but underexploited potential drug target.

**Figure 2.** Schematic of molecular and chemical approaches used to target major IE gene expression and IE protein function. Key groups of molecules are listed by category, and examples of molecules within each category given in italics. DGN, deguelin; NZT, nitazoxanide; TGN, thioguanosine; AXN, alexidine dihydrochloride; MND, manidipine dihydrochloride.
