**Alexander Bader \*, Finn Meiners and Kirsten Tracht**

Bremen Institute of Mechanical Engineering (BIME), University of Bremen, Badgasteiner Str. 1, 28359 Bremen, Germany; meiners@bime.de (F.M.); tracht@bime.de (K.T.)

**\*** Correspondence: bader@bime.de; Tel.: +49-421-2186-4839

Received: 5 July 2018; Accepted: 30 July 2018; Published: 1 August 2018

**Abstract:** High-throughput screenings are widely accepted for pharmaceutical developments for new substances and the development of new drugs with required characteristics by evolutionary studies. Current research projects transfer this principle of high-throughput testing to the development of metallic materials. In addition to new generating and testing methods, these types of high-throughput systems need a logistical control and handling method to reduce throughput time to get test results faster. Instead of the direct material flow found in classical high-throughput screenings, these systems have a very complex structure of material flow. The result is a highly dynamic system that includes short-term changes such as rerun stations, partial tests, and temporarily paced sequences between working systems. This paper presents a framework that divides the actions for system acceleration into three main sections. First, methods for special applications in high-throughput systems are designed or adapted to speed up the generation, treatment, and testing processes. Second, methods are needed to process trial plans and to control test orders, which can efficiently reduce waiting times. The third part of the framework describes procedures for handling samples. This reduces non-productive times and reduces order processing in individual lots.

**Keywords:** micro-manufacturing; manufacturing systems; production planning
