*2.12. Statistical Analysis*

Data are presented as means ± SEM. Statistical significance was evaluated using Prism Graph Pad (San Diego, CA, USA) using an unpaired two-tailed Student's *t*-test, Mann–Whitney test, or a

one-way ANOVA. The BN-PAGE analysis was conducted with a repeated one-way ANOVA analysis. Differences were considered to be statistically significant when *P* < 0.05.
