**5. Conclusions**

Markers of systemic changes in the cerebellar metabolism of amino acids were introduced, showing decreased reactivity of the pregnancy-changed amino acids network to metabolic stress, such as acute hypobaric hypoxia.

**Author Contributions:** A.G.: methodology, investigation (animal experiments), data curation, formal analysis, writing–review & editing; L.T.: investigation (animal experiments, sample preparation, enzyme assay), methodology; A.K.: investigation (ninhydrine quantification of amino acids), methodology; L.B.: methodology; V.B.: investigation (combining animal experiments with biochemical assays), methodology, formal analysis, writing–original draft, review & editing, supervision, project administration, funding acquisition. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was funded by Russian Science Foundation gran<sup>t</sup> number N 18-14-00116 to Victoria I Bunik.

**Acknowledgments:** We thank E. Kulakovskaya (Faculty of Biology, Moscow Lomonosov State University) and G. Mkrtchyan (Faculty of Bioengineering and Bioinformatics, Moscow Lomonosov State University, currently at University of Copenhagen, Denmark) for technical assistance with sample preparation.

**Conflicts of Interest:** The authors declare no conflict of interest.
