**4. Discussion**

In the context of global warming, academic communities have paid increasing attention to the direct and indirect effects of climate change on the appearance and spread of infectious diseases. The relationship between climate change and infectious diseases has become an important research field, which requires the systematic analysis of the knowledge structure and theme trends. In this study, the bibliometric analysis, co-word biclustering analysis, and strategic diagram on the scientific productions from the quantitative and content's points of view were integrated to investigate the knowledge structure and evolution of this field in the past 20 years.
