**4. Conclusion**

Two new compounds, the somewhat unprecedented nitrogen containing (4*R*\*,5*R*\*,9*S*\*,10*R*\*,11*Z*)-4-methoxy-9-((dimethylamino)-methyl)-12,15-epoxy-11(13)-en-decahydronaphthalen -16-ol (**1**) and the lobane (1*R\**,2*R\**,4*S\**,15*E*)-loba-8,10,13(14),15(16)-tetraen-17,18-diol-17-acetate (**2**), together with the eight known compounds sarcophytol-B [24], (1*E*,3*E*,7*E*)-11,12-epoxycembratrien-15-ol [8], loba-8,10,13(15)-triene-16,17,18-triol [25], 14,18-epoxyloba-8,10,13(15)-trien-17-ol [26], lobatrientriol [7], lobatrienolide [7], 14,17-epoxyloba-8,10,13(15)-trien-18-ol-18-acetate [26] and (17*R*)-loba-8,10,13(15)-trien-17,18-diol [27], were isolated from the Australian soft coral *Sinularia* sp. Although there are many publications detailing the isolation of lobanes [6,7] and cembranes [8,9,11] from soft corals of the genus *Sinularia*, this report shows that new investigations are still yielding further new and somewhat unprecedented derivatives, and that continued investigations of this genus are warranted. The biological and pharmacological properties associated with soft coral chemistry, in particular terpenoids, have been shown to be highly promising [30], leading to the need for more extensive structure-activity relationship studies and further evaluation of their mechanism of action.

**Acknowledgments:** Collection of this soft coral was made possible through the access and benefit sharing arrangements between AIMS and the Australian Commonwealth Government. The authors are grateful to those AIMS staff, both past and present, involved in the collection. We thank A.-M. Babey, School of Veterinary and Biomedical Sciences, James Cook University for initial cytotoxicity screening data and for the SF-268 cell line and C. Hooi, R. Anderson and C. Cullinane, of the Peter MacCallum Cancer Centre, Melbourne, Australia, for the MCF-7 and H460 cell lines.
