*3.2. The Practical Issues with the Use of BoNT-A in Treating IC*/*BPS*

Although BoNT-A is now widely used to treat IC/BPS, it still is a novel treatment that has only been included in guidelines since 2015 [2]. Clinical evidence is still relatively limited, and several technique details of BoNT-A injection to IC/BPS patients remain unclear. The following sections list the practical issues that should be noticed by clinicians, and summarize current evidence of the debatable issues.
