**1. Introduction**

Chronic prostatitis describes a constellation of complaints such as pain in the perineum, genitalia, pelvis, or lower abdomen, ejaculation pain, or irritative/voiding urinary symptoms [1,2]. In 1995, National Institutes of Health (NIH) developed a consensus on the general definition and classification of prostatitis, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) as the "presence of genitourinary pain in the absence of uropathogenic bacteria as detected by standard microbiologic methodology" [3]. This disease has negatively affected the quality of life in 5–10% of the adult males of North America; however, the etiology is still largely unknown [4,5].
