**Supplementary Materials:** Supplementary materials can be found at http://www.mdpi.com/1422-0067/21/5/1819/s1.

**Author Contributions:** Conceptualization, X.F. (Xiaorong Fan); Data curation, X.F. (Xiaoru Fan) and J.C.; Formal analysis, X.F. (Xiaoru Fan); Funding acquisition, X.F. (Xiaorong Fan); Investigation, X.F. (Xiaoru Fan); Methodology, Y.W.; Project administration, X.F. (Xiaorong Fan); Resources, X.F. (Xiaorong Fan); Supervision, G.X. and X.F. (Xiaorong Fan); Writing – original draft, X.F. (Xiaoru Fan) and X.F. (Xiaorong Fan); Writing – review & editing, X.F. (Xiaoru Fan), J.C., Y.W., C.T. and X.F. (Xiaorong Fan). All authors have read and agreed to the published version of the manuscript.

**Funding:** This work is supported by China National Key Program for Research and Development (2016YFD0100700), National Natural Science Foundation (Grant 31372122), the Transgenic Project (Grant 2016ZX08001003-008), the 111 Project (Grant 12009), Innovation project of basic scientific research in central Universities of Ministry of Education (KYYJ201604, KJJQ201701), Innovative Research Team Development Plan of Ministry of Education of China (IRT\_17R56; KYT201802), Jiangsu Science and Technology Development Program (Grant BE2019375-1).

#### **Conflicts of Interest:** The authors declare no conflict of interest.

**Availability of Data and Materials:** The WGBS and MeDIP dataset created for this publication are available in the NCBI GEO repository with accession number GSE94319.
