*2.4. Magnetic Resonance Imaging (MRI) Acquisition*

After a mock scanner training session, magnetic resonance imaging (MRI) was performed using a Siemens MAGNETOM Prismafit 3 Tesla MRI scanner (Siemens Medical Systems) with a 20-channel phased array coil. A high-resolution magnetic resonance imaging scan was acquired using a T1-weighted three-dimensional magnetization prepared rapid gradient echo (MP-RAGE) sequence with the parameters: 256 <sup>×</sup> 256 <sup>×</sup> 176-matrix size with 1 <sup>×</sup> 1 <sup>×</sup> 1-mm<sup>3</sup> resolution; inversion time <sup>=</sup> 900 ms; repetition time (TR) = 1950 ms; echo time (TE) = 2.26 ms; flip angle = 90◦; Total scan duration was 4 min and 14 s. A diffusion weighted image was acquired using a dual spin echo, single shot, pulsed gradient, echo planar imaging sequence in 64 diffusion sensitized gradient directions with the following parameters: TR = 8100 ms; TE = 69 ms; flip angle = 90◦; 70 axial slices; 2 mm × 2 mm × 2 mm voxel size; FOV = 256 mm; *b* value = 1000 s/mm2; Total scan duration was 9 min and 29 s.
