*2.1. Anxiolytics*

No ecotoxicological data was found in literature for ALP, LOR and ZOL, and for that reason, all the results for this therapeutic group were obtained from ECOSAR 2.0 [18]. In decreasing order, the more toxic was ZOL, followed by ALP and LOR. The trophic level with the lowest reported concentrations producing toxicity was algae (from 0.211 to 6.07 mg L−1), followed by fish (from 0.248 to 43.1 mg <sup>L</sup>−1) and invertebrates (from 1.55 to 39.4 mg <sup>L</sup>−1).
