**Appendix A**

**Table A1.** Toxicity of the selected antidepressants in the Spirotox assay [mg/L].



**Table A2.** Concentration of the tested antidepressants in *S. ambiguum* in μg/g.


**Table A3.** Bioconcentration factor of the tested antidepressants in *S. ambiguum* in L/kg. The test was performed in duplicate.


**Table A4.** MS/MS optimized conditions for the analyzed compounds and internal standards.

*CE*-collision energy; *DP*-declustering potential; *CXP*-collision cell exit potential.
