*2.11. Statistical Analysis*

All data shown in the graph are expressed as mean ± SEM. All experiments were performed using at least three different cultures or animals in independent experiments. A statistical analysis was performed using two-tailed unpaired Student's t-Test, one-way ANOVA or two-way ANOVA. \* *p* < 0.05; \*\* *p* < 0.01; \*\*\* *p* < 0.001; confidence intervals 95%, alpha level 0.05.

#### **3. Results**
