*4.3. [18F]NaF Production*

The 2-mL solution of [18F]F<sup>−</sup> in enriched water was manually applied to a preconditioned Sep-Pak Light QMA cartridge (WAT023525, Waters, Zellik, Belgium). The QMA was rinsed with 3 mL of water and [18F]NaF was eluted with 300 μL of 0.9% NaCl solution (typically 5 GBq is eluted). The eluate was diluted with water to obtain a 10 MBq/μL solution.
