*Article* **One-Pot Iridium Catalyzed C–H Borylation**/ **Sonogashira Cross-Coupling: Access to Borylated Aryl Alkynes**

**Ghayoor A. Chotana 1,2, Jose R. Montero Bastidas 1, Susanne L. Miller 3, Milton R. Smith III 1,\* and Robert E. Maleczka Jr. 1,\***


Academic Editors: José Pérez Sestelo and Luis A. Sarandeses Received: 4 March 2020; Accepted: 3 April 2020; Published: 10 April 2020

**Abstract:** Borylated aryl alkynes have been synthesized via one-pot iridium catalyzed C–H borylation (CHB)/Sonogashira cross-coupling of aryl bromides. Direct borylation of aryl alkynes encountered problems related to the reactivity of the alkyne under CHB conditions. However, tolerance of aryl bromides to CHB made possible a subsequent Sonogashira cross-coupling to access the desired borylated aryl alkynes.

**Keywords:** C–H borylation; Sonogashira cross-coupling; borylated aryl alkynes; one-pot reaction
