*4.5. Statistical Analysis*

All data is presented as mean ± SEM. Statistical analysis was conducted with GraphPad Prism 7.0d software (San Diego, CA, USA) using the unpaired two-tailed Student's t-test. Significance was determined if *p* values were < 0.05.

**Author Contributions:** Conceptualization: R.C.S., D.J.K., and S.T.H.; data curation: R.C.S., T.M.B., A.L.K., F.K.K., P.D., A.L., J.D.B., C.J.M., S.Z., D.J.K., and S.T.H.; formal analysis: R.C.S., T.M.B., D.J.K., and S.T.H.; funding acquisition: D.J.K. and S.T.H.; investigation: R.C.S., T.M.B., D.J.K., and S.T.H.; methodology: R.C.S., D.J.K., and S.T.H.; project administration: D.M., D.J.K., and S.T.H.; resources: R.C.S., T.M.B., A.L.K., F.K.K., P.D., A.L., J.D.B., C.J.M., S.Z., D.J.K., and S.T.H.; software: R.C.S., D.J.K., and S.T.H.; supervision: D.J.K. and S.T.H.; validation: T.M.B., D.J.K., and S.T.H.; visualization: R.C.S., T.M.B., D.J.K., and S.T.H.; writing—original draft: R.C.S.; writing—review and editing, R.C.S., T.M.B., C.E.B., D.J.K., and S.T.H.

**Funding:** This research was funded by a Harmful Algal Bloom Research Initiative grant from the Ohio Department of Higher Education, the David and Helen Boone Foundation Research Fund, the University of Toledo Women and Philanthropy Genetic Analysis Instrumentation Center, and the University of Toledo Medical Research Society.

**Conflicts of Interest:** The authors declare no conflict of interest.

#### **References**


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