**3. Results and Discussion**

Eight putative actinobacterial endophytes, designated as ADR1 to ADR8, were isolated from the plant, *Datura metel*. While no isolate could be found from the stem part of the plant, six were obtained from the root tissues and two were from the leaves. The antibacterial potency of these isolates was examined against the reference strain, *S. aureus* ATCC 25923. Based on the size of the zone of inhibition, the isolate ADR1 was chosen for further studies as it produced largest zone (22.5 ± 0.58 mm). Production of the metabolites by ADR1 was carried out under the conditions as described under Section 2.3. The metabolite extract was recovered as red colour hygroscopic sticky mass (approximately 120 mg/L).
