3.2.1. Disc Diffusion Method

Antagonistic characteristics of the bioactive extract of *Streptomyces* sp.S2A showed potent antagonistic activity against bacterial and fungal pathogens (Table 1). Of six bacterial pathogens, the highest inhibition activity was manifested against *Micrococcus luteus* and *Staphylococcus epidermidis* (16 mm). Susceptibility of *Bacillus cereus*, *Klebsiella pneumoniae* and *Staphylococcus aureus* to bioactive compounds was highly noticeable (14 mm). *Escherichia coli* was less susceptible to the compound (10 mm). Among fungal pathogens, reduction in mycelial growth was not seen against *Aspergillus flavus* and *Alternaria alternata* whereas inhibitory activity was significantly observed against *Fusarium moniliforme* and *Bipolaris maydis* (See Supplementary Figure S1).

