*2.3. Electron Beam Melting*

EBM is a modern fast solution to manufacture metal parts on a layer-by-layer basis through an electron beam that, bombarding the metal powders, melts them, constructing 3D geometries. This technique compared with ones using a laser, are characterized by high energy utilization and material absorption rate, improved stability, and reduced maintenance fees [54]. Although this technique is successfully used for the realization of porous orthopedic and dental implants made of metallic biomedical alloys as Ti6Al4V [55], to date, there are no applications of EBM for the production of 3D printed mesoporous devices for drug delivery application. This is due to the fact that these kinds of scaffolds are characterized by large surface roughness since EBM microfabrication accuracy ranges from 0.3–0.4 mm.
