*3.5. Sensitivity Analyses*

Our results were robust to sensitivity analyses, including complete case analyses without correction for potential selection bias, as well as RTN–MGRS interaction analyses excluding asthmatic participants Sensitivity analyses limited to participants whose bedrooms were oriented towards the street also showed very similar results. Interactions with self-reported sleep insufficiency were consistent in diabetic participants, reaching significance among those on medication. Unlike with MGRS, we observed significant interaction with self-reported sleep sufficiency in non-diabetic individuals (Table 4).

*MTNR1B* score represents the sum of risk alleles across six included variants. All estimates represent an increase (+) or decrease (−) in mean change in HbA1c per 10 dB of night-time road traffic noise. Adjusted models included age, sex, education, neighborhood socio-economic index, smoking status, passive smoking, alcohol consumption, body mass index, green space within a 2 km residential buffer, residential levels of nitrogen dioxide, night-time railway, aircraft noise, and their truncation indicators. All models include random intercepts at the level of the study areas, and were adjusted for potential selection bias by applying the probability of participation in present analyses as weights derived from a logistic regression with predictors from the baseline study in 1991. NA: not applicable.



### *Int. J. Environ. Res. Public Health* **2017**, *14*, 1492
