*3.3. Discomfort Analysis*

The perception of the discomfort caused by the lesion before the laser therapy results, on average, in the scale selected for the measurement of this parameter, approximate to zero. The discomfort perceived during the treatment stands at average values (between 2.5 and 2.0) and tends to decrease less evidently in the short term, while in the medium to long term it follows a decreasing trend from values of 2.6 at T0 to 1.9 at T4. The values show that on average the variable assumes significant values for all observations and that the trend decreased particularly between the second and third week of treatment. The discomfort was always described as a burning sensation (Figure 3).

**Figure 3.** Trend of discomfort perceived throughout the treatment. The data were divided as follow: discomfort felt before the patient was subjected to treatment, during irradiation of the lesion and in the days following the session. The data refer to the entire month of observation.
