**5. Conclusions**

In conclusion, irregular immigrants appear to be a population with a high prevalence of LTBI and active TB and risk of progression from LTBI to active TB, being also characterized by delays in diagnosis and impaired referral to the health services. Consequently, they should be actively targeted with appropriate screening and follow-up procedures, particularly for selected subgroups showing lower compliance with screening and follow-up. Because of the high probability of diagnostic delay and poor accessibility to health services, systematic active TB screening should be implemented in each clinic dealing with seeking care irregular immigrants. In addition, the simultaneous execution of both the TB and LTBI screenings may optimize allocation and use of the resources.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/1660-4601/16/1/28/s1, Table S1: Demographic characteristics of the study population. Table S2: Association between countries of origin, sex and compliance with screening for active tuberculosis (TB), screening for latent tuberculosis infection (LTBI) and the full protocol (multivariate analysis). Table S3: Association between selected characteristics and compliance with Tuberculin Skin Test (TST) reading (bivariate and multivariate analysis). Table S4: Association between selected characteristics and compliance with chest-X-ray (CXR) execution (bivariate and multivariate analysis). *Int. J. Environ. Res. Public Health* **2019**, *16*, 28

Table S5: Association between selected characteristics and compliance with Quantiferon-TB gold (QFT) execution (bivariate and multivariate analysis). Table S6: Association between selected characteristics and outcome of Latent Tuberculosis Infection (LTBI) treatment (bivariate analysis).

**Author Contributions:** Conceptualization, B.F., C.S. and V.M.; Methodology, B.F., C.S., F.R. and V.M.; Software and Formal Analysis, B.F., C.S. and V.M.; Validation, V.M.; Investigation and Resources, B.F., F.R., C.C., G.M., M.L., M.C. and N.F.; Data Curation, B.F., C.S. and V.M.; Writing—original draft preparation, B.F., C.S., and V.M.; Writing—Review and Editing, B.F., C.S., F.R., C.C., M.C., G.M., M.L., N.F., and V.M.; Visualization, B.F., C.S., V.M.; Supervision and Project Administration, B.F. and V.M.; Funding Acquisition, V.M.

**Funding:** Funding provided by the Local Health Unit of Reggio Emilia.

**Acknowledgments:** In this section you can acknowledge any support given which is not covered by the author contribution or funding sections. This may include administrative and technical support, or donations in kind (e.g., materials used for experiments).

**Conflicts of Interest:** The authors declare no conflict of interest.
