**5. Conclusions**

On the basis of our results, laser-assisted treatment can be considered successful. In the future it will be possible to recruit more patients in order to correlate systemic factors, such as diabetes, anaemia or gastroesophageal reflux, with the effects of the treatment in order to evaluate if those factors influence the result of the therapy. Another aspect to consider could be the rate of recurrence and malignant transformation in a longer follow-up; in this study we follow the patients for only one month after the end of the treatment and no significant differences were found since the last irradiation.

In conclusion we can state that the treatment is a valid alternative to conventional surgery with a scalpel if the lesion is bigger than 8 mm, below this limit it is better to completely eliminate the lesion during a biopsy. Lesions with a maximum size of 2 cm can regress during the four sessions set, obviously the larger the lesion, the more time needed to allow the lesion to regress.

**Author Contributions:** Conceptualization, D.L.; Data curation, A.L.; Investigation, F.G. and J.S.R.; Supervision, F.C.; Visualization, D.D.S.

**Funding:** This research received no external funding.

**Conflicts of Interest:** The authors declare no conflict of interest.
