**6. Conclusions**

In this large and well-selected cohort of patients affected by DCM, the rate of LVRR was similar between males and females. However, females achieving LVRR experienced a more favourable long-term prognosis and male sex has been confirmed as independently associated to adverse prognosis even after the LVRR is achieved. A precise characterization of DCM, including genetic background, will be essential to explain this difference in outcomes between men and women in the future.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/2077-0383/9/8/2426/s1, Figure S1: The model consists of three discrete health states (i.e., alive without LVRR; alive with LVRR; dead or HTx or VAD) and a transition probability matrix (P) is calculated between states.

**Author Contributions:** Conceptualization, A.C., P.M., V.N. and M.M.; methodology, A.C., P.M., V.N., C.G., J.A., P.G., G.B., M.M.; software, A.C., C.G., G.B.; validation, A.C., P.M., V.N., C.G., J.A., P.G., C.P.L., G.B., M.M.; formal analysis, A.C., P.M., C.G., G.B.; investigation, A.C., M.M., G.S.; resources, M.M., G.S.; data curation, A.C., C.P.L., F.R., M.M.; writing-original draft preparation, A.C., P.M., M.M.; writing-review & editing, A.C., P.M., V.N., C.G., J.A., P.G., C.P.L., G.B., M.M.; visualization, C.G.; supervision, M.M., G.S. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Acknowledgments:** We would like to thank Fondazione CRTrieste, Fondazione CariGO, Fincantieri and all the healthcare professionals for the continuous support to the clinical management of patients affected by cardiomyopathies, followed in Heart Failure Outpatient Clinic of Trieste, and their families.

**Conflicts of Interest:** The authors declare no conflict of interest.
