2.2.1. Preparation of the Polymer Blends

All the polymeric blends were based on: PUL, CH and CA; PUL, CH and CA containing CS or HA. PUL solution was prepared in distilled water and CS or HA were added to PUL, thus preparing three different solutions: PUL; PUL/CS and PUL/HA. N, as a free drug, or loaded in a hybrid system (H) (nanocomposite based on VHS and N [8]), was mixed with PUL, PUL/CS or PUL/HA. Then, CH was hydrated in acetic acid and CA was added. Three different polymeric blends were prepared by mixing each PUL, PUL/CS, and PUL/HA with CH solution at 1:1 weight ratio and norfloxacin concentration was 0.15% or 0.30% *w*/*w*, respectively, corresponding to 1% or 2% *w*/*w* in dry systems, after electrospinning. The composition of the blends prepared is reported in Table 1.


**Table 1.** Quali-quantitative composition of polymeric blends.
