2.1.2. Changes in sCyst-C after Exercises Shorter than a Marathon

Poortmans et al. found that after a 30-min treadmill test at 80% of the maximal oxygen capacity, sCyst-C increased significantly by 13% (from 0.91 ± 0.06 to 1.03 ± 0.09 mg/L) and eGFR -Cyst-C decreased significantly by 19.8% [25]. Another study concerning subjects performing a submaximal test on a cycle ergometer at an exercise intensity of 80% of the maximal heart rate was performed by Bongers et al. In contrast to Poortmans, they did not find any changes in eGFR -Cyst-C after 30 min of exercise (eGFR 118 vs. 116 mL/min/1.73 m2), but after 150 min of exercise, a significant decrease in eGFR -Cyst-C to 103 mL/min/1.73 m2 was observed [26]. In Poortmans' and Bongers' studies, only males of the similar age (25 and 23 years) were studied. The difference between these two studies can be related to the type of exercise—in Poortmans' study, a run on a treadmill, and in Bongers' study, cycling on an ergometer [25,26].
