5.1.1. SCr

SCr concentrations are widely used to assess kidney function. However, accumulating evidence indicates that measurements of SCr levels do not always detect kidney disease early, and individual variability in SCr generation rates limits the utility of these tests in terms of identifying and assessing the severity of kidney injury [25]. Furthermore, UUTO often affects the unilateral upper urinary tract. The contralateral kidney can compensate for the loss of renal function.
