7.3.4. Diabetes Mellitus

In a study of urinary levels of enzymes and low-molecular-mass proteins as indicators of diabetes nephropathy, Jung et al. [141] observed an increase in urinary alanine aminopeptidase in diabetic patients and an even greater increase in diabetic patients with proteinuria. However, a study by Lazarevic et al. [106] on the impact of aerobic exercise on microalbuminuria and enzymuria in type II diabetic patients found no significant difference in urinary or plasma APN activities over the study period between patients with and without diabetes or within the diabetes group. Numerous factors may be implicated in these discrepancies between studies.
