*4.5. RT-qPCR*

To quantify circulating lncRNA levels we performed RT-qPCR. Isolated RNA was reverse transcribed using Iscript (Biorad) according to the protocol of the manufacturer. RT-qPCR of target genes was done using SYBR Green Master Mix (Applied Biosystems, Waltham, MA, USA). The primer sequences of target lncRNAs are given in Supplementary Table S2.
