*4.8. Statistical Analysis*

All values are expressed as mean ± SEM. Between-group comparisons were determined by the unpaired Student's *t*-tests or ANOVA, followed by Tukey's post hoc multiple comparison test. Statistical analysis was performed using the Statistical Analysis System (SAS, Version 9.4, SAS Institute, Cary, NC, USA). A value of two-sided *p* < 0.05 was considered statistically significant.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/1422-0067/21/17/5966/s1, Figure S1. The effect of trichostatin A (TSA) on the activation of renal fibroblasts.

**Author Contributions:** Conceptualization, W.-C.T.; data curation, M.-T.T.; formal analysis, W.-C.T. and M.-T.T.; funding acquisition, W.-C.T. and D.-C.T.; investigation, W.-C.T.; methodology, W.-C.T.; project administration, D.-C.T.; resources, D.-C.T.; supervision, N.-J.C. and D.-C.T.; validation, M.-T.T.; writing—original draft, W.-C.T. and writing—review and editing, M.-T.T., N.-J.C. and D.-C.T. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported in part by the Ministry of Science and Technology (grant numbers MOST 102-2314-B-010-004-MY3, MOST 105-2314-B-010-016, MOST 106-2314-B-010-039-MY3 and MOST 107-2314-B-075-064-MY3); the Taipei Veterans General Hospital (grant numbers V105C-013, V106C-147, V107C-127, V107-B-037, V108-C-175 and V108-C-103); the Department of Health, Taipei City Government (grant numbers 10401-62-010 and 10501-62-006); the Taipei City Hospital (grant numbers TPCH-105-031 and TPCH-106-034); Foundation for Poison Control; the Ministry of Education's Aim for the Top University Plan in the National Yang-Ming University, Taiwan and the Center For Intelligent Drug Systems and Smart Bio-devices (IDS2B) from the Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan.

**Acknowledgments:** The authors thank the Division of Experimental Surgery, Department of Surgery and Department of Pathology, Taipei Veterans General Hospital for technical assistance. They also thank the Clinical Research Core Laboratory and the Medical Science & Technology Building of Taipei Veterans General Hospital for providing experimental space and facilities.

**Conflicts of Interest:** The funding sources had no role in the study design, conduct or reporting. The authors declare that they have no conflicts of interest.
