*4.1. Patients*

A total of 34 CKD patients participated in the study (Table 1). Diagnosis of diabetic nephropathy patients was made clinically by the presence of diabetes; most patients had hypertension. Hypertensive nephropathy was diagnosed clinically by the presence of hypertension without presence of diabetes; no biopsy was performed in these groups. A group of glomerulonephritis patients were diagnosed by biopsy. All participants signed an informed consent. The study was approved by the Ethical Committee of the Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky (ethical code 88/2019 of 27 February 2019).
