*4.9. Statistical Analysis*

Statistical analyses were performed using one-way ANOVA in GraphPad Prism software (GraphPad Software Inc., La Jolla, CA, USA). *p* < 0.05 was considered statistically significant.

**Author Contributions:** Designed the experiments: P.Q., H.C. and X.L.; Performed the experiments: G.H. and H.Z.; Analyzed the data: G.H. and P.Q.; Wrote the paper: G.H. and H.Z.; Proofed the manuscript: P.Q., H.C. and X.L. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by the National Program on Key Research Project of China (2018YFD0500801, 2018YFD0500204), the Fundamental Research Funds for the Central Universities (2662016PY003), the Technology Base and Talents Special Program of Guangxi Province (2018AD09007) and the Natural Science Foundation of Hubei Province (2019CFA010).

**Conflicts of Interest:** The authors declare no conflict of interest.
