CH2Cl2–MeOH

(10:1) ė preparative ODS HPLC (MeOH)). A total of 0.3 mg (04OKA-13-27) and 0.5 mg (YM6-073) of pure carotenoids were obtained from the cells of each 2 liter culture, and the carotenoids were identified as (3*R*)-saproxanthin (04OKA-13-27) (**5**) and (3*R*,2<sup>ȝ</sup>*S*)-myxol (YM6-073) (**6**) by MS, 1H-NMR, and CD analyses, respectively (Figure 3). 

The antioxidative activities of compounds **5** and **6** were examined using rat brain homogenate model. Compounds **5** and **6** showed potent antioxidant activities (IC50 2.1 ΐM (**5**) and 6.2 ΐM (**6**)) 

(IC50 10.9 ΐM (Ά-carotene)). 

> **Figure 3.** The structures of (3*R*)-saproxanthin (**5**) and (3*R*,2<sup>ȝ</sup>*S*)-myxol (**6**).
