*4.3. HBV*

CPXV012 peptide affected HBV infection as measured by a decrease in viral DNA and viral antigen in the supernatant of infected cultures. HBV particles are thought to acquire their envelope from multivesicular bodies [58], which are rich in PS [59]. The role of PS in HBV infection is underlined by studies showing that antibodies specific for PS block HBV infection [60]. Similar to poxviruses, PS may play a role in virus entry through apoptotic mimicry [61,62]. PS may also play a role in the proper folding of HBV envelope proteins [63].
