*2.4. Viruses*

Zaire ebolavirus rec/COD/1976/Mayinga-rgEBOV (GenBank accession number KF827427.1), which is identical in sequence to the EBOV Mayinga isolate with the exception of four silent mutations as genetic markers [33], was used for all infection experiments. rgEBOV was propagated in VeroE6 cells and virus titers were determined by 50% tissue culture infectious dose (TCID50) assay. All work with the infectious virus was performed under BSL-4 conditions at the Friedrich-Loe ffler-Institut (Federal Research Institute of Animal Health, Greifswald Insel-Riems, Germany) following approved standard operating procedures.
