**Non-Carbon 2D Materials-Based Field-E**ff**ect Transistor Biosensors: Recent Advances, Challenges, and Future Perspectives**

#### **Mohammed Sedki 1,**†**, Ying Chen 2,**† **and Ashok Mulchandani 2,\***


Received: 12 July 2020; Accepted: 24 August 2020; Published: 26 August 2020

**Abstract:** In recent years, field-effect transistors (FETs) have been very promising for biosensor applications due to their high sensitivity, real-time applicability, scalability, and prospect of integrating measurement system on a chip. Non-carbon 2D materials, such as transition metal dichalcogenides (TMDCs), hexagonal boron nitride (h-BN), black phosphorus (BP), and metal oxides, are a group of new materials that have a huge potential in FET biosensor applications. In this work, we review the recent advances and remarkable studies of non-carbon 2D materials, in terms of their structures, preparations, properties and FET biosensor applications. We will also discuss the challenges facing non-carbon 2D materials-FET biosensors and their future perspectives.

**Keywords:** 2D-materials; field-effect transistor; transition metal dichalcogenides; black phosphorus; phosphorene; hexagonal boron nitride; transition metal oxides; biosensors
