**6. Patents**

The work is covered by the following licensed patent families: Formulations and composites with reactive fillers (US8252851 B2, EP2066703B1, US20100069469, WO2008037991A1), and Formulations and materials with cationic polymers (PCT/GB2014/052349, WO2015015212 A1, EP3027164A1, US20160184190).

**Author Contributions:** Conceptualization, N.N.L., E.A., W.X., P.F.A., A.M.Y.; Methodology, N.N.L., E.A., W.X., P.F.A., A.M.Y.; Validation, N.N.L., E.A., P.F.A., A.M.Y.; Formal Analysis, N.N.L.; Investigation, N.N.L.; Resources, N.N.L., E.A., P.F.A., A.M.Y.; Writing—original Draft Preparation, N.N.L.; Writing—review & Editing, N.N.L., E.A., P.F.A., A.M.Y.; Supervision, E.A., W.X., P.F.A., A.M.Y.; Project Administration, A.M.Y.; Funding Acquisition, A.M.Y. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was funded by National Institute for Health Research (Invention for Innovation (i4i, http://www.nihr.ac.uk/funding/invention-for-innovation.htm)); Optimization and commercial manufacture of tooth-coloured composite dental-fillings with added poly-antimicrobial (PAM) and remineralising calcium phosphate (CaP), II-LB-0214-2002) (WX), UK EPSRC (Engineering and Physical Sciences Research Council, https://www.epsrc.ac.uk) (EPI/I02234/1)(WX); and Welcome Trust (Wtissf 3: Institutional Strategic Support Fund (Issf) Third Tranche, www.wellcome.ac.uk/Funding/WTP057769.htm) (WX).

**Conflicts of Interest:** In the future the corresponding author and inventor on the above patents (Anne Young) may receive royalties when a commercial product is produced. This author has had funding from NIHR and EPSRC and is working with Schottlander Dental Company to optimize a similar product to those in the publication.
