**5. Conclusions**

In this in vitro study, the newly developed dentin desensitizer demonstrated e ffective dentinal tubules sealing capability and promoted mineral crystal growth over dentin and into the tubules during simulated body fluid storage. For bonding to the desensitizer-treated dentin, dentin treatment by two-step self-etching system or universal bond with phosphoric acid is recommended.

**Author Contributions:** Conceptualization: A.S.; methodology: M.N.L., L.H.; image interpretation: A.S., M.N.L.; formal analysis: A.S.; resources: A.S. and D.C.N.C.; writing—original draft preparation: M.N.L.; writing review and editing: A.S. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research and APC charges were supported by the Biomimetics Biomaterials Biophotonics Biomechanics & Technology (B4T), Department of Restorative Dentistry, University of Washington, Seattle, WA, USA.

**Acknowledgments:** Authors are grateful to the manufacturers of materials Parkell and Kuraray Noritake Dental for their donation of the experimental materials.

**Conflicts of Interest:** The authors declare no conflict of interest with regard to the authorship of this manuscript.
