*3.1. Co-Crystal Synthesis*

The size of the co-crystals produced was smaller than that of the starting compounds when using the bottom up approach and the size reduction yielded sub-micron crystals. The uncoated micro cocrystals have a PS of 1593 ± 148 nm, PDI of 0.751 ± 0.063 and ZP of -6.86 ± 1.04 mV. The characterization of these crystals is reported herein.
