*2.1. Materials*

AZT and 3TC were purchased from China Skyrun Co. Ltd. (Taizhou, China). Tween ® 80, Span ® 80, SDS and TPGS 1000 were purchased from Merck (Johannesburg, South Africa). HPLC-grade water was prepared by reverse osmosis using a RephiLe ® Direct-Pure UP and RO water system Microsep ® (Johannesburg, South Africa) fitted with a RephiDuo ® H PAK de-ionization cartridge and a RephiDuo ® PAK polishing cartridge. The water was filtered through a 0.22 μm PES high flux capsule filter Microsep ® (Johannesburg, South Africa) prior to use. HPLC grade Honeywell Burdick and Jackson ™ methanol (MeOH) was purchased from Anatech Instruments (Johannesburg, South Africa).
