*2.1. Materials*

AZT and 3TC were purchased from China Skyrun Co. Ltd. (Taizhou, China). SDS and TPGS 1000 were purchased from Merck (Johannesburg, South Africa). HPLC-grade water was prepared by reverse osmosis using a RephiLe® Direct-Pure UP and RO water system Microsep® (Johannesburg, South Africa) fitted with a RephiDuo® H PAK de-ionization cartridge and a RephiDuo® PAK polishing cartridge. The water was filtered through a 0.22 μm PES high-flux capsule filter Microsep® (Johannesburg, South Africa) prior to use. HPLC-grade methanol (MeOH) was purchased from Honeywell Burdick and Jackson™ (Anatech Instruments, Johannesburg, South Africa).
