3.1.1. RIV for Compaction Study

A saturated solution of RIV was prepared by dissolving the drug (~6.0 g) in acetonitrile (600 mL) with magnetic stirring the solution on a heated water bath at 60-65 ◦C for 30 min followed by cooling at room temperature (RT). The resultant solution was kept for slow solvent evaporation at room temperature. Columnar-shaped, small-sized crystals, generated within 1-2 h, were collected by vacuum filtration and subjected to air drying.
