3.1.4. Formulation Optimization

The desired target level for each input variable and associated responses PS, PDI and ZP are summarised in Table 7. The desirability of the model generated was 1.000, indicating that the optimum conditions were located in the desirability zone. The optimum formulation composition for the manufacture OPT-NCC and is summarised in Table 7.


**Table 7.** Formulation variables and associated responses.

The responses generated using the NCC formulation developed and manufactured according to the optimum composition are summarised in Table 8, in addition to the experimental and predicted responses with the corresponding percent prediction error.

**Table 8.** Summary of results for the NCC produced using optimum formulation parameters.

