**2. Materials and Methods**

The 1-hydroxy-4,5-dimethyl-imidazole 3-oxide (**1**) was obtained employing the procedure reported in the literature [17]. Compounds **2** and **3** were purchased from Sigma Aldrich (Poznan, Poland) and used without further purification. Reagent grade solvents were purchased from Polish Chemicals Reagents (POCH) company (Gliwice, Poland).

*2.1. Preparation of Thiobarbituric Acid*/*1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide (TBA*/*HIMO) Cocrystal*
