*3.5. Kidney Fibrosis*

Recently, the Wnt pathway in the kidney has gained attention because of its association with renal fibrosis. In the kidney, pericytes are recognized as collagen-producing cells [34]. Once a kidney injury is established, pericytes migrate to the interstitial space where they di fferentiate into scar-forming myofibroblasts [34]. In this context, the Wnt pathway is markedly activated in pericytes at the time they di fferentiate into myofibroblasts, which may cause fibrosis of the kidney interstitium [35].
