*5.6. Physical Inactivity*

Both the drivers (e.g., obesity) and consequences (e.g., anemia, cardiovascular disease, malnutrition) of CKD may be associated to physical inactivity and this may act as a chronodisruptor. The impact of regular physical activity on kidney functions circadian misalignment should be studied, since regular endurance exercise appears to entrain peripheral clocks in muscle and heart [52].
