*4.5. Statistical Analyses*

Data were analyzed by one-way ANOVA or two-way ANOVA and Tukey post hoc test or T test using GraphPad Prism software version 7.00 (GraphPad, San Diego, CA, USA, 2016). Values are expressed as means ± SEM. Statistical significance was considered when *p* < 0.05.

**Author Contributions:** Conceptualization, H.D.M.C., I.R.A.d.M., R.P., and S.V.; methodology, L.B.R.D., A.L.M.S., I.S.A., A.O.B.P.B.M., and F.R.S.P.; validation, C.P.d.S.J.; formal analysis, M.R.C.d.O.; resources, L.J.Q.-J.; writing—original draft preparation, J.R.-F., writing—review and editing, J.R.F. and L.B.R.D. supervision, H.D.M.C., I.R.A.d.M., R.P., and S.V. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES), Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico (FUNCAP) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)–finance code 304291/2017-0 and Financiadora de Estudos e Projetos-Brasil (FINEP).

**Acknowledgments:** The authors would like to thank the support and resources provided by the Leão Sampaio University Center (Juazeiro do Norte, Brazil).

**Conflicts of Interest:** The authors declare no conflict of interest.
