*2.1. General Information*

Epigallocatechingallate (EGCG), trolox (6-hydroxyl-2, 5, 7, 8- tetramethylchroman-2-carboxylic acid), and other reagents, including 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) diammonium salt, potassium peroxodisulphate, fluorescein sodium salt, 2,2-Azobis (2-methylpropionamidine) dihydrochloride (AAPH), perchloric acid, 2,4,6-tri[2-pyridyl]-s-triazine (TPTZ), iron (III) chloride hexahydrate, copper sulphate, hydrogen peroxide, α-glucosidase (*Saccharomyces cerevisiae*), α-amylase (procaine pancreas), 3,5-dinitro salicylic acid (DNS), p-nitro-phenylα-D-glucopyranoside (p-NPG), sodium carbonate (Na2CO3), sodium dihydrogen phosphate, and di-sodium hydrogen phosphate, secured and purchased from Sigma-Aldrich, Cape town, South Africa.

Organic solvents, methanol (HPLC grade), ethanol, ethyl acetate, and hexane, were supplied by Merck (Cape Town, South Africa). Thin layer chromatography (TLC) as conducted on normal-phase (Merck) Silica gel 60 PF254 pre-coated aluminum plates. Column chromatography was performed using silica gel 60 H (0.040–0.063 mm particle size, Merck, Cape Town, South Africa) and Sephadex LH-20 (Sigma-Aldrich, Cape Town, South Africa).

NMR spectra were recorded on an Avance 400 MHz NMR spectrometer (Bruker, Rheinstetten, Germany) in deuterated chloroform and acetone, using the solvent signals as the internal reference. HRMS analysis was conducted on an Ultimate 3000 LC (Dionex, Sunnyvale, CA, USA) coupled to a Bruker QTOF with an electrospray ionization (ESI) interface working in the positive ion mode. Preparative HPLC was used for further isolation of pure compounds using HPLC methanol and distilled water.
