*2.10. Statistical Analysis*

All values are expressed as mean ± SD of at least three independent experiments, as indicated in figure legends. After normality tests, comparisons between di fferent treatments were analyzed by a one-way ANOVA tests. Values of *p* < 0.05 were considered statistically significant for a post-hoc Tukey's test. All statistical tests were done using the software Graph-Pad Prism version 7.01. Degrees of significance are indicated in the figure captions as follow: \* *p* < 0.05; \*\* *p* < 0.01; \*\*\* *p* < 0.001, \*\*\*\* *p* < 0.0001, ns = not significant.
