*3.3. Merged ZIKV PIN*

We combined the final Y2H and TAP-MS networks to generate the Merged ZIKV Network containing 157 nodes (including the baits) with 189 interactions between NS proteins and human host proteins (Figure 3A) (Table S4). Only 3 out of 151 hits were common to both Y2H and MS-based networks (BCLAF1, AHCYL1, and COPB1), indicating a limited overlap between methods.
