Reprint
From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
Edited by
March 2021
188 pages
- ISBN978-3-0365-0112-3 (Hardback)
- ISBN978-3-0365-0113-0 (PDF)
This book is a reprint of the Special Issue From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials that was published in
Chemistry & Materials Science
Engineering
Summary
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage—the first step in carcinogenesis—must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
graphene oxide; reduced graphene oxide; micronucleus; oxidative stress; safer-by-design; tungsten; nanoparticles; tritiated particles; in vitro testing; cytotoxicity; micronuclei formation; DNA damage; epigenetics; DNA methylation; BEAS-2B cells.; polystyrene nanoparticles; nanoplastics; genotoxicity; Hs27 human fibroblasts; comet assay; FPG enzyme; TiO2NP; SiO2NP; ZnONP; CeO2NP; AgNP; multi-walled carbon nanotubes (MWCNT); titanium dioxide nanoparticles; lincomycin; human amniotic cells; in vitro genotoxicity; apoptosis; DNA damage; nanotoxicology; genotoxicity; DNA damage; metal oxides; high throughput screening; genotoxicity; comet assay; micronucleus assay; nanomaterial; aluminum; oral route; gut; liver; titanium dioxide nanoparticles; V79 cells; genotoxicity; Hprt; advanced in vitro model; comet assay; genotoxicity; hepatotoxicity; liver spheroids; nanoparticles; 3D culture; HepG2; nongenotoxic silver nanoparticles; genotoxic; cytotoxic; antioxidant activity; silver ions; Allium cepa; metal/coating agent ratio; n/a