*3.5. Preparations of the (S)- and (R)-MTPA Esters of Compounds 7 and 8*

To a solution of compound **7** (0.6 mg, 1 μM) in dry pyridine (500 μL), (*S*)-MTPA chloride (10 μL, 5.2 μM) and DMAP (0.5 mg) were successively added. After stirring for 3 h at 40 ◦C under N2, the reaction mixture was concentrated under reduced pressure, and the residue was purified by reversed-phase HPLC (YMC-ODS column, 4.6 × 250 mm; H2O-MeCN, 73:27) to give **7**-4*R* (0.3 mg), the (*R*)-MTPA ester of **7**. Compound **7**-4*S* (0.3 mg), the (*S*)-MTPA ester of **7**, was prepared from (*R*)-MTPA chloride in a similar fashion. Compounds **8**-2*S* and **8**-2*R* (0.3 mg each), the (*S*)- and (*R*)-MTPA esters of **5**, respectively, were also prepared using this method.
