**5. Conclusions**

This survey identifies health status, health monitoring and sheep provider as starting points for refinement in the use of sheep for biomedical research. This is in line with the harmonized, progressive definition of refinement [6].

**Supplementary Materials:** The following are available online at http://www.mdpi.com/2076-2615/10/9/1528/s1, Figure S1: Survey Sheep English version, Figure S2: Survey sheep French version.

**Author Contributions:** Authors were involved as following in the different parts of this study: conceptualization: C.M.B., U.L. and S.Z., methodology: C.M.B., U.L. and S.Z., formal analysis: C.M.B., writing—original draft preparation, C.M.B., writing—review and editing: C.M.B., U.L. and S.Z., supervision: U.L. and S.Z., project administration: C.M.B., funding acquisition: S.Z. All authors have read and agreed to the published version of the manuscript.

**Funding:** This investigation was financially supported with the assistance of the AO Foundation via the AO Strategy Fund Project number 13. No external funds were received in support of this work.

**Acknowledgments:** The authors would like to thank the SGV, the ECLAM, the ESLAV, the Swiss Animal Welfare O fficers Network, the AFSTAL and the VOLE list for kindly accepting to distribute the questionnaire, all the participants and Jean Pierre Cabassu for his grea<sup>t</sup> support.

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design, execution, interpretation, or writing of the study.
