*3.1. Clinical Characteristics*

Clinical characteristics of the subjects are presented in Table 1.

Interestingly, hyposalivation was observed in all patients with severe renal failure (4–5 stage CKD), while saliva secretion >0.2 mL/min in children with mild-moderate CKD (1–3 stage) and controls.



ACEI—Angiotensin-converting enzyme inhibitors; C—Healthy controls; CCB—Calcium channel blockers; CKD NS—CKD patients with normal salivary secretion; CKD HS—CKD patients with reduced salivary secretion; NA—not applicable; NWS—Non-stimulated whole saliva; eGFR—estimated glomerular filtration rate; Hct—Hematocrit; Hgb—Hemoglobin.
