*Review Candida* **Infection Associated with Salivary Gland—A Narrative Review**

**Soo-Min Ok 1,2,3, Donald Ho 3, Tyler Lynd 3, Yong-Woo Ahn 1,2, Hye-Min Ju 1,2, Sung-Hee Jeong 1,2 and Kyounga Cheon 3,\***


Received: 29 November 2020; Accepted: 26 December 2020; Published: 30 December 2020

**Abstract:** *Candida* species are common global opportunistic pathogens that could repeatedly and chronically cause oral mucosa infection and create an inflammatory environment, leading to organ dysfunction. Oral *Candida* infections may cause temporary or permanent damage to salivary glands, resulting in the destruction of acinar cells and the formation of scar tissue. Restricted function of the salivary glands leads to discomfort and diseases of the oral mucosa, such as dry mouth and associated infection. This narrative review attempts to summarize the anatomy and function of salivary glands, the associations between *Candida* and saliva, the effects of *Candida* infection on salivary glands, and the treatment strategies. Overall, clinicians should proactively manage *Candida* infections by educating patients on oral hygiene management for vulnerable populations, conducting frequent checks for a timely diagnosis, and providing an effective treatment plan.

**Keywords:** oral candidiasis; salivary gland; saliva; treatment
