**3. Data Analysis and Statistics**

Data are presented as the mean +/−standard error of the mean (SEM) from a minimum of three separate experiments. Significant results were calculated using Student's *t*-test on GraphPad Prism 8 (San Diego, CA, USA). *P*-values were determined to be significant using the Holm–Šidák post hoc test for multiple comparisons with alpha = 0.05.
