*7.3. pSS-Associated Lymphoma*

The occurrence of lymphoma is a complication that must be screened clinically, especially in patients at risk (see above). Any appearance of a firm, painless glandular swelling must be investigated if it does not disappear spontaneously. The exams of choice to detect lymphoma are an MRI of the major SG and a CT of chest, abdomen and pelvis for staging or a PET scan to investigate the entire body in a single examination. pSS patients with lymphoma require personalized treatment provided by an oncohematologist according to the histological type, the extent of the involvement and the systemic manifestations.
