*7.4. Obstetrical Considerations*

Ideally, pSS patients of childbearing age should benefit from a preconception consultation aimed at reviewing their treatment and their serological profile (anti-Ro/SSA, anti-La/SSB and antiphospholipid panel). Low-dose aspirin can be considered to promote placental implantation [319]. Anti-Ro/SSA positive mothers should be followed regularly by foetal ultrasound in a specialized centre [210,319]. Prophylactic treatment of neonatal atrioventricular block with hydroxychloroquine may be offered, since this drug is compatible with pregnancy [210]. If a conduction disorder appears on a follow-up ultrasound, rescue therapy with glucocorticoid with or without IVIG may be attempted [210]. In the event of atrioventricular block at birth, a pacemaker must be quickly implanted.
