**7. Conclusions**

This systematic review aimed to examine the treatment outcomes in cannabis pharmacological interventions for women and men. In addition, it analyzed the uptake of sex- and gender-based analysis in pharmacological interventions for cannabis use. Despite the increasing evidence showing that sex and gender factors intervene in patterns of cannabis use, health effects and biological mechanisms, we found only four articles that sex-disaggregated the outcomes for both sexes on CUD treatment. Taking into account the poor uptake of sex- and gender-based analysis, future research should consider more consistent and disciplined integration of sex and gender in cannabis pharmacological interventions in order to improve outcomes for all individuals experiencing CUD.

**Author Contributions:** Conceptualization, A.C.B. and L.G.; methodology, A.C.B., N.H. and J.S.; data curation, A.C.B. and N.H.; writing—original draft preparation, A.C.B.; writing—review and editing, A.C.B., L.G., N.H. and J.S.; funding acquisition, L.G. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was funded by Canadian Institutes of Health Research, Team Grant: Impact of Gender on Knowledge Translation Interventions (Evaluating the Effectiveness of Sex- and Gender-Based Analysis on Knowledge Translation Interventions).

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

### **References**


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International Journal of *Environmental Research and Public Health*
