Search 3: April 2018

After identifying multiple papers relevant to our review that were not being captured by the original searches, we conducted a third search in April 2018. Based on analysis of the keywords in the articles that were missed, we amended the search as follows:

1. The following terms were added to the gender/sex terms:

(woman or man or women or men or girl or boy or girls or boys or trans or transgender or transgendered or female or male or sex or gender). ti. [GENDER IN TI]

A search was then conducted of the article titles only, combining the following concepts:

Search strategy:

Concept 1—Gender/sex terms

AND

Concept 2—Substances (opioids, alcohol, tobacco, cannabis) terms

AND

Concept 3—Harm reduction, health promotion, prevention, treatment, health effects terms


## **Appendix B. Final Inclusion Criteria**

## *Study Design:*


Note:


The following types of literature will be included in the grey literature review:


Note: magazines and books will be excluded from the grey literature.
