**3. Results**

Table 1 shows demographic and clinical characteristics of the 205 pediatric HHT patients comprising our cohort, as well as the phenotype characteristics by genotype. Our cohort was 47% female with an average age of 9.9 years. There was no significant di fference in the distribution of age or sex between the three genotypes. Among the 205 patients, 176 (85.9%) had epistaxis, 107 (52.2%) had typical mucocutaneous telangiectases, 62 (30.2%) had at least one pulmonary AVM, seven (3.4%) had symptomatic liver VMs, and 70 (34.1%) had one or more brain VM. There was evidence of GI bleeding in nine patients (4.4%) and 30 patients (14.6%) were anemic.
