*2.4. Image Normalization*

MR image intensities are acquired in arbitrary units, introducing noise when comparing scans taken at different times. To compensate for artifacts between scans, each MR and DW sequence were normalized across the patient set. Standard MR sequences were normalized using the RAVEL method [45] implemented with the intensity-normalization library [46]. The DW sequence was normalized using MRtrix's dwiintensitynorm.
