**Preface to "Cells and Materials for Disease Modeling and Regenerative Medicine"**

Materials science and engineering are strongly developing tools with increasing impact in the biotechnological and biomedical areas. Interestingly, research in molecular and cellular biology is often at the core of the design and development of materials-based approaches, providing biological rationale.

Focused on research relying on biology–materials interaction, IJMS launched a Special Issue named "Cells and Materials for Disease Modeling and Regenerative Medicine". The aim of the Special Issue was to generate a compilation of in vitro and in vivo strategies based on cell–material interactions. This book compiles the papers published in that Special Issue and includes a selection of six original scientific experimental articles and six comprehensive reviews.

Often, tissue regeneration is the final goal of materials developed for biomedical applications. For this purpose, the regenerative approaches need to be designed considering targeted tissue properties and their regenerative mechanisms. Moreover, materials must be biocompatible and, if possible, bioactive. In this Special Issue, the relevance of materials development in regenerative medicine is highlighted, and several papers have been selected as representative of current research in this field:


In this Special Issue book, disease modeling was also considered as an essential research field in the study of materials for biomedical applications. In this sense, five papers were included as representative of the heterogeneity and, at the same time, versatility of this area:


Altogether, we are convinced that this collection of articles shows representative examples of the state of the art in the field, unveiling the relevance of materials research in generating new regenerative medicine and disease modeling approaches.

> **Ander Abarrategi, Senentxu Lanceros-Mendez**

*Editors*
