*3.1. Materials*

Poly(vinylidenefluoride-co-trifluoroethylene); P(VDF-TrFE), with 70 mol% vinylidene fluoride and 30 mol% trifluoroethylene, from Solvay (Póvoa de Santa Iria, Portugal); and N,N-dimethylformamide, DMF, from Merck (Sintra, Portugal), were used as received. An 8% (*w*/*w*) polymer solution in DMF was prepared under magnetic stirring at room temperature.

#### *3.2. Samples Processing and Main Characteristics*

Patterned scaffolds were obtained through photolithography and replica molding techniques, as described in [7,24]. In short, lines and hexagonal patterns with different dimensions (25, 75, and 150 μm) were designed in AutoCAD 2018 software and printed in photolithographic masks by Microlitho (see supplementary information—Figures S2 and S3). The photolithographic masks were used for the fabrication of SU-8 patterned molds, through photolithography, which were replicated in flexible and reusable polydimethylsiloxane (PDMS) molds, through replica molding. The P(VDF-TrFE) in DMF polymer solution was deposited on both patterned and non-patterned PDMS molds, previously treated with an oxygen plasma for 10 min, and evaporated at 100 ◦C [25]. The obtained samples present hydrophobic behavior (>100◦) and a crystallinity degree of ≈ 32%, as shown previously [7].
