*4.6. Statistics*

All results are expressed as medians with interquartile ranges (25–75%) and whiskers. As this is the first study on this topic, no a priori power calculation could be performed. Testing for statistical significance was done by one- or two-way ANOVA. *p*-values ≤ 0.05 were seen as significant. All statistical analyses were performed with GraphPad Prism Version 7 (GraphPad Software, San Diego, CA, USA).

**Author Contributions:** Conceptualization, J.W., M.D. and A.J.-H.; Data curation, J.W., A.S. (Armin Springer) and M.F.; Funding acquisition, M.D., R.B. and A.J.-H.; Investigation, J.W., A.S. (Anika Seyfarth) and A.S. (Armin Springer); Methodology, J.W., A.S. (Anika Seyfarth) and M.F.; Project administration, R.B. and A.J.-H.; Resources, M.D., M.F. and R.B.; Supervision, M.D., R.B. and A.J.-H.; Writing—original draft, J.W., M.D. and A.J.-H.; Writing—review & editing, A.S. (Anika Seyfarth), A.S. (Armin Springer), M.F. and R.B., J.W. takes responsibility for the integrity of the work as a whole, from inception to finished article. All authors have read and agreed to the published version of the manuscript.

**Funding:** This joint research project HOGEMA is supported by the European Social Fund (ESF), reference: ESF/14-BM-A55-0012/18, and the Ministry of Education, Science and Culture of Mecklenburg-Vorpommern, Germany.

**Acknowledgments:** We thank Brigitte Mueller-Hilke, Michael Mueller, and Wendy Bergmann (Core Facility for Cell Sorting and Cell Analysis, Center for Medical Research, University Medical Center Rostock, Germany) for instruction and for providing the devices. We also thank Karoline Schulz and Ute Schulz (Medical Biology and Electron Microscopy Center, University Medical Center Rostock) for excellent technical support.

**Conflicts of Interest:** The authors declare no conflict of interest.
