*8.7. mRNA Therapy*

Moderna (https://www.modernatx.com/), a clinical stage biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, have developed mRNA-3283, that encodes the human *PAH* to restore the intracellular enzyme activity in patients with PKU at an effective dose amount encapsulated within a liposome nanoparticle; mRNA-3283 is currently in preclinical development.
