**2. Materials**

The kidney biopsies dataset analyzed in this paper has been provided by the Department of Emergency and Organ Transplantations (DETO) of the Bari University Hospital. Slides were digitized using a high-resolution whole-slide scanner with a scanning objective which has a 20× magnification corresponding to a resolution of 0.50 μm/pixel. All the biopsies provided by DETO clinicians are PAS stained sections from formalin fixed paraffin embedded tissue. The complete dataset is composed of 26 kidney biopsies coming from 19 donors. It contains 2344 non-sclerotic glomeruli and 428 sclerotic glomeruli. The dataset has been split into a train-validation (trainval) set and a test set. The trainval set has been further split into a train set and a validation set; the last one is used for tuning hyperparameters and for assessing the trend of the loss function and of accuracy during the training process. A detailed overview of the dataset is reported in Table 1.


