*Article* **Description and In-Vitro Test Results of a New Wearable**/**Portable Device for Extracorporeal Blood Ultrafiltration** †

**Paolo Boscariol 1, Giovanni Boschetti 1, Aldo Dalla Via 1, Nicola De Rossi 1, Mauro Neri 1,2, Ilaria Palomba 3, Dario Richiedei 1, Claudio Ronco 2,4 and Alberto Trevisani 1,\***


Received: 15 April 2019; Accepted: 31 May 2019; Published: 4 June 2019

**Abstract:** This paper presents the design of Rene Artificiale Portatile (RAP), a novel wearable and portable device for extracorporeal blood ultrafiltration, capable of providing remote treatment of fluid overload in patients with kidney diseases and/or congestive heart failure. The development of the device is based on a new design paradigm, since the layout of the device is box-shaped, as to fit a backpack or a trolley case, di fferentiating it from other existing devices. The e fficient layout and component placement guarantee minimalization and ergonomics, as well as an e fficient and cost-e ffective use. The redundant control architecture of the device has been implemented to ensure a high level of safety and an e ffective implementation of the clinical treatment. The consistency of the design and its e ffective implementation are assessed by the results of the preliminary in-vitro tests presented and discussed in this work.

**Keywords:** wearable device; blood ultrafiltration; mechatronic device; renal replacement
