**4. Conclusions**

This series of papers is noteworthy because the identification of the factors that predispose to a long and healthy life is of enormous interest for translational medicine.

**Author Contributions:** Both authors (C.C. and A.A.P.) wrote. Both authors have read and agreed to the published version of the manuscript.

**Funding:** The original work of the Authors in the topic was supported by 20157ATSLF project (Discovery of molecular, and genetic/epigenetic signatures underlying resistance to age-related diseases and comorbidities), granted by the Italian Ministry of Education, University and Research.

**Conflicts of Interest:** The authors declare no conflict of interest.

#### **References**

