*2.5. Data Processing and Analysis*

Data collection at room temperature or cryogenic temperature required the use of multiple crystals to obtain a complete set of data. The crystals were screened on plates A and B, 20 crystals were selected at room temperature and 10 crystals were selected at cryogenic temperature for data collection. Each dataset was indexed by XDS [23], and then imported into the BLEND program [24] in CCP4 [25], and then we combined each dataset for integration and homogenization. We selected the best combination of data from several sets of data according to the quality of the data. The method of structure determination was adopted from the molecular replacement program CCP4, the search model of lysozyme was from the PDB1rcm of the protein database, and then Phenix [26] was used to refine the structure. The final model was modified by Coot [27].
