*Editorial* **Paediatric Formulation: Design and Development**

### **Antonio Lopalco \* and Nunzio Denora \***

Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy

	- Tel.: +39-080-544-2764 (A.L.); +39-080-544-2767 (N.D.)

Received: 28 August 2020; Accepted: 25 September 2020; Published: 27 September 2020

**Abstract:** The development of medicines designed for children can be challenging since this distinct patient population requires specific needs. A formulation designed for paediatric patients must consider the following aspects: patient population variability; dose flexibility; route of administration; patient compliance; drug and excipient tolerability. The purpose of this Special Issue entitled "Paediatric Formulation: Design and Development" is to provide an update on both state-of-the-art methodology and operational challenges in the design and development of paediatric formulations. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; e fficacy, safety, and tolerability of drugs and excipients. This editorial, briefly, summarizes the objects of nine original research and review papers published in this Special Issue.

**Keywords:** formulation; development; design; children; paediatric; age-related; palatable; taste-masking; acceptable; excipient
