*4.11. Statistical Analysis*

All experiments were performed at least three times. The data are presented as means ± S.E.M. Statistical significance was performed by using Student's t test, and *p* < 0.05 was considered statistically significant.

**Supplementary Materials:** Supplementary materials can be found at http://www.mdpi.com/1422-0067/21/10/ 3546/s1.

**Author Contributions:** M.-Y.L. and W.-K.H. carried out experiments, analyzed data and prepared the figures in the paper. W.-J.L. contributed to experimental design, analysis, interpretation of data and writing of the paper. C.-J.C. contributed to insightful discussion, data interpretation and the writing of the paper. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by the Ministry of Science and Technology (grant No: MOST 107-2320-B-010-039 to W.-J.L. and MOST 108-2320-B-010-017 to W.-J.L.)

**Acknowledgments:** We thank the current and former members of the group for their technical support in experiments.

**Conflicts of Interest:** The authors declare no conflict of interest.
