*2.3. Identification of Flavoring Additives by GC-MS-O Analysis*

GC-MS-O methodology was revealed to be a powerful approach for accurate identification of volatile odor-active compounds in high-level complexity matrices through coupling traditional chromatographic analysis with human sensory perception [36–38]. For this reason, GC-MS-O methodology was applied in the present study, allowing us to accurately identify, on a limited number of e-liquids, the odor-active compounds responsible for the overall flavor perceived or of specific flavor notes.
