*2.8. Cluster Analysis of DEGs*

Based on the screening of DEGs with under criteria of an FDR < 0.05 and log2FC| > 1, 786 DEGs were screened from the SF-Sel strain, 557 of which were upregulated, while 229 were downregulated compared with those in the Lab-Sus strain (Figure 3A,B).

**Figure 3.** (**A**) The statistical maps of DEGs among S-vs-M. (**B**)The cluster heat maps of DEGs among S-vs-M. The column represents samples, and the row means genes; Color-scaled represents log 2 (fold change) values for resistant lines, the redder the color is, the higher the gene expression is, and on the contrary, the greener color is.
