**5. Conclusions**

Summing up the conducted research, one must conclude that, despite a noticeable decrease in the average annual number of culturable microorganisms in the atmospheric aerosol in the south of Western Siberia, the hazard of these bacteria and yeasts to humans has not practically changed for 10 years. Thus, neither passing climatic changes in the world, nor changes in the antibiotic resistance and sustainability of culturable microorganisms in the environment have a ffected the hazard to humans of bacteria and yeasts found in the atmospheric aerosol in the south of Western Siberia.

The authors published in 2012 [28] an approach on how to estimate the hazard of bacteria and yeasts in atmospheric aerosols to humans, but no similar investigation has been conducted elsewhere in the world. Usually, the data of experiments are given in the literature, in which the e ffect of a specific bioaerosol that has penetrated the respiratory tract is studied, see, for example [104]. It is clear that such an approach is di fficult to use to characterize a large number of bioaerosol samples. The authors hope that very important studies on risks of human exposure to microorganisms in the air will be estimated using our approach [28] and will be published, not only for Western Siberia; the authors also hope that a longer study of the properties of culturable microorganisms in atmospheric aerosols will reliably confirm the identified weak dependencies in the future in the south of Western Siberia.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/1660-4601/17/5/1651/s1, Table S1: Sustainability of culturable microorganisms in the environment. Site of the FBRI SRC VB "Vector", Table S2: Sustainability of culturable microorganisms in the environment. Site Klyuchi, Table S3: Sustainability of culturable microorganisms in the environment. Aircraft sounding of the atmosphere, Table S4: Hazard of culturable microorganisms in the atmospheric aerosol. Site of the FBRI SRC VB "Vector", Table S5: Hazard of culturable microorganisms in the atmospheric aerosol. Site Klyuchi, Table S6: Hazard y of culturable microorganisms in the atmospheric aerosol. Aircraft sounding of the atmosphere, Table S7: Indices of culturable bacteria and yeas<sup>t</sup> resistance to antibiotics. Site of the FBRI SRC VB "Vector", Table S8: Indices of culturable bacteria and yeas<sup>t</sup> resistance to antibiotics. Site Klyuchi, Table S9: Indices of culturable bacteria and yeas<sup>t</sup> resistance to antibiotics. Aircraft sounding of the atmosphere, Table S10: Number of isolates in the samples. Site of the FBRI SRC VB "Vector", Table S11: Number of isolates in the samples. Site Klyuchi, Table S12: Number of isolates in the samples. Aircraft sounding of the atmosphere. Table S13: Integral index and data analysis.

**Author Contributions:** Conceptualization and methodology, A.S., M.P.; Investigation, B.B., O.O., D.S., S.O., I.R., G.B., I.A., L.P., N.S.; data analysis, A.S., G.B.; writing—original draft preparation, A.S.; writing—review and editing, A.S., G.B.; project administration, A.S. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was partially funded by Russian Federation Rospotrebnadzor, gran<sup>t</sup> number 141-00069-18-01.

**Conflicts of Interest:** The authors declare no conflict of interest.
